SIN3A staining in tissue sections of the SIN3A-WT coincided with cancer lesions observed in clusters similar to the staining of the mutant SIN3A (Fig. 5A,B), but SIN3A staining was strongly detected within the nuclei under magnified imaging, and the nuclear staining of hematoxylin disappeared due to the staining overlapped with SIN3A staining (Fig. 5C). Here, SIN3A is linked to cancer.