We also detected alterations in other G1 regulators in the ALK+ ALCL cell lines when JunB was knocked-down including decreased expression of cyclin-dependent kinase 2 (CDK2) in both Karpas 299 and SUP-M2 cells, as well as reduced levels of cyclin E in SUP-M2 cells. This evidence concerns the gene CDK2 and anaplastic large cell lymphoma.