We observed enhanced control of MuHV-4-luc-CSP infection in the lung by day 7 pvi which was associated with an increased response of effector CSP280–288-specific CD8+ T responses (Fig. 5g), further supporting that TVM are conditioned by exposure to helminths, which could explain the enhanced effector responses against their cognate Ag. Here, DNAJC5 is linked to infection.