SGCB and respiratory failure: Our findings in a newborn animal model for neonatal pulmonary vascular disease suggests that sGC stimulators/activators could be of benefit as a novel treatment strategy to stop or even reverse neonatal pulmonary vascular disease and/or PH, especially since the use of iNO for preterm infants with respiratory failure is currently under debate (Barrington and Finer 2007; Askie et al.