S100B and tongue cancer: However, this was not the case in other studies in colorectal cancer (Dadabayev et al. 2004) and also in breast, gastric, ovarian, and tongue carcinomas (Goldman et al. 1998; Lespagnard et al. 1999; Okuyama et al. 1998; Eisenthal et al. 2001; Iwamoto et al. 2003).In melanoma patients, increased serum S-100Β levels (Schultz et al. 1998) correlated with clinical stage, prognosis, and survival.