Moreover, higher expression levels of NEAT1 were positively correlated with cancer stage and metastasis in endometrial cancer (Li Z. et al., 2016), ovarian cancer (Chen Z. J. et al., 2016), non-small cell lung cancer (Pan et al., 2015; Sun et al., 2017), hepatocellular carcinoma (Sun et al., 2016), esophageal squamous cell carcinoma (Chen et al., 2015), laryngeal squamous cell cancer (Wang P. et al., 2016), breast cancer (Zhao et al., 2017), gastric cancer (Fu et al., 2016), and osteosarcoma (Hu et al., 2018). This evidence concerns the gene NEAT1 and esophageal squamous cell carcinoma.