Similarly, the inhibition of NEAT1 via siRNA reduced cancer cell proliferation, migration and invasion in esophageal squamous cell carcinoma, endometrial cancer, glioma, hepatocellular carcinoma and renal cell carcinoma (Chen et al., 2015; Li Z. et al., 2016; Zhen et al., 2016; Ning et al., 2017; Wang Z. et al., 2017). This evidence concerns the gene NEAT1 and central nervous system cancer.