Finally, tear expression of CCL3 was reported to be increased in DE patients compared to healthy control subjects, especially in those with SS (87) and CCR5 receptor of CCL3 is positively correlated with HLA-DR in conjunctival cells of patients (88); it is also known also that CCL3 shows a significant distribution in salivary of pSS compared to non-SS sicca (89). This evidence concerns the gene CCL3 and synovial sarcoma.