TP53 and Parkinson disease: Other transcripts involved in the intrinsic apoptosis pathway (Jin and El-Deiry, 2005) that were suppressed by L. braziliensis exposure included TP53, which encodes tumor protein 53 or p53, and LRRK2, the major late-onset familial Parkinson’s disease associated gene [also called PARK 8 (Paisan-Ruiz et al., 2004; Zimprich et al., 2004)].