Tomasik et al. studied probiotic in schizophrenia and found their significant impact in reducing von Willebrand factor and increasing brain-derived neurotrophic factor (BDNF), monocyte chemotactic protein-1 (MCP-1), T-cell-specific protein RANTES, and macrophage inflammatory protein-1 beta (MIP-1) beta. This evidence concerns the gene VWF and schizophrenia.