Moreover, the eight new colon CTC lines did not express endothelial proteins (CD31 and CD105), hematopoietic progenitor markers (CD34) and C-X-C chemokine receptor type 4 (CXCR4), a receptor expressed on breast tumor cells and involved in the chemoattraction to specific organs16 (Supplementary Table S4). Here, CD34 is linked to breast neoplasm.