GAS5 and neoplasm: The well-characterised tumour suppressor of GAS5 has been documented in a wide variety of human malignancies and loss of GAS5 expression has been implicated both in tumorigenesis and disease progression,16,17 as well as in patients prognosis.18,19 A dual complementary function in arresting cell growth by inhibition of cell proliferation and stimulation of apoptosis has been attributed to GAS5, highlighting an active role in growth arrest rather than a passive association.