Three of seven established NHGRI-EBI asthma SNPs and three of five pediatric asthma SNPs from the TAGS GWAS were associated with self-reported childhood asthma, including SNPs in IL1RL1, IL13, near the C11orf30-LRRC32 region, in LINC01149, and near GSDMB. Additionally, GWAS identified one variant in KIAA1958 that was associated with childhood asthma among NHWs with genome-wide significance. Here, GSDMB is linked to childhood onset asthma.