When all potential confounding factors were adjusted, serum MMP9 was still significantly associated with AAA risk (OR = 1.004 per unit increase, 95% CI = 1.001–1.007, P = 0.018) and TAA risk (OR = 1.014 per unit increase, 95% CI = 1.006–1.022, P < 0.001). The gene discussed is MMP9; the disease is triple-A syndrome.