Guo and colleagues identified a signature of differentially methylated genes (AGTR1, GALR1, SLC5A8, ZMYND10, and NTSR1) as biomarkers for non-small cell lung cancer (NSCLC) diagnosis by integrating three high-throughput DNA methylation microarray datasets including 458 samples (352 NSCLC and 106 normal tissues) from GEO (Gene Expression Omnibus) and TCGA [41]. The gene discussed is NTSR1; the disease is non-small cell lung carcinoma.