In order to evaluate the differences of PLP2 expression between glial cell and glioma cell lines, higher PLP2 expression was identified on all glioma cell lines than the SV40-immortalized human fetal glial cell line SVG p12 by western-blot analysis (** p < 0.01; *** p < 0.001, Figure 1B). This evidence concerns the gene PLP2 and central nervous system cancer.