PRKAB1 and glycogen storage disease V: A mouse model of McArdle’s disease containing a p.R50X mutation, a nonsense mutation of nucleotide 148 in exon 1 of the GP gene, showed increased basal AMPK phosphorylation in the tibialis anterior and quadriceps muscles, associated with an increased GLUT4 content and increased AMPK-mediated glucose uptake compared to WT [95].