An increasing number of potential LRRK2 phosphorylation targets involved in PD pathogenesis has been identified in the studies that used the fly model of LRRK2-linked PD, including the glycogen synthase kinase 3b (GSK 3b) [125], microtubule-binding protein 1B (MAP1B) homolog Futsch [141], endophilin A (EndoA) [142,143], eukaryotic initiation factor 4E-binding protein (4E-BP) [124], and ribosome protein s15 [144]. The gene discussed is RPS15; the disease is Parkinson disease.