SPP1 and colorectal carcinoma: In line with our previous findings, postoperative osteopontin serum levels were unaltered between patients with moderately (G2) or poorly (G3) differentiated tumours (Supplementary Figure S2a), left- or right-sided primary CRC (Supplementary Figure S2b) and KRAS mutated or wildtype CRC (Supplementary Figure S2c).