ELOVL4 and psoriasis: Earlier studies have revealed five genes essential for psoriasis development: PPARD, GATA3, TIMP3, WNT5A and PTTG1. 34 In the present study, we also found an altered expression of PPARD, GATA3 and WNT5A. As a corollary, we note that a PPARβ/δ agonist has recently been shown to induce CERS3 and ELOVL4 in cultured keratinocytes.35