Several of the induced AMP genes may also alter keratinocyte differentiation and proliferation.25 Our findings are reminiscent of the situation in lesional psoriatic skin,25 except that the expression of Rnase7, LL‐37 and dermcidin was not induced in the ARCI patients with TGM1 mutations. This evidence concerns the gene RNASE7 and autosomal recessive congenital ichthyosis.