The somatic mutations gene list (GATA3, ESR1, TBX3, RUNX1, NCOR1, KMT2C, SPEN, ARID1A, NOTCH2, MAP2K4, RB1, MTOR, MED12, and LRP1B) was selected from somatic mutations in the cancer (COSMIC) database. The gene discussed is NCOR1; the disease is cancer.