In acute myeloid leukemia cells, lower levels of Bach1 expression were associated with increases in HO-1 levels and in cell viability after exposure to an anticancer drug [29], and CXCR3-B appears to inhibit the growth of breast cancer cells by promoting the nuclear localization of Bach1, which subsequently suppresses HO-1 [57]. This evidence concerns the gene BACH1 and breast carcinoma.