PPARA and Arthritis: More specifically, molecules related to Role of Macrophages, Fibroblasts and Endothelial Cells in Rheumatoid Arthritis (Arthritis); Hepatic Cholestasis, Hepatic Fibrosis/Hepatic Stellate Cell Activation, PPAR Signaling (Metabolism); and INOS Signaling (Immunology) were increased, suggesting that chronic presence of NOD may possibly lead to the development of pathway-indicated pathologies (Supplementary Figure 1 and Figure 6C).