Other less frequent coexistent pairs of point mutation (e.g. G12D and G12C, G12V and G12C) could be a consequence of two additional mutations in cells of one clone or coincident KRAS mutation in the neighboring epithelial cells that subsequently developed additional cell clone co-forming NSCLC, an example of the parallel carcinogenesis. The gene discussed is KRAS; the disease is non-small cell lung carcinoma.