In vivo testing using human breast cancer xenograft tumors up to 7 days post‐biomaterial implantation:No effect on tumor growth ratesNo significant changes in tumor necrosis, hypoxic cell number (CA9), proliferation (Ki67), apoptosis (caspase 3), immune cell (neutrophil, macrophage), and fibroblast infiltration or collagen deposition. The gene discussed is CA9; the disease is neoplasm.