PAK2 and pancreatic ductal adenocarcinoma: A recent report has shown that in pancreatic ductal adenocarcinoma, PKM2 could phosphorylate the serine/threonine protein kinase PAK2 at Ser20, Ser141, and Ser 192/197 to recruit heat shock protein 90 for increasing the stability of the PAK2 protein, thereby promoting invasion and metastasis of the pancreatic cancerous cells [21].