In the next step, we examined the roles of IFN-γ and IL-6 in the pulmonary pathophysiology of DM RP-ILD by immunostaining and hematoxylin-eosin (H&E) staining of lung tissues, hilar lymph nodes, and spleen tissues from two patients from whom specimens were obtained on autopsy (Fig. 3). The gene discussed is IFNG; the disease is dermatomyositis.