It has been reported that Ang-(1–7) has its anti-inflammatory effects in arthritis and allergic airway through the Mas receptor [12, 13] and decreases lipopolysaccharide (LPS)-stimulated proinflammatory cytokines, including tumor necrosis factor-α and interleukin 6 (IL-6), in mouse peritoneal macrophages [14]. This evidence concerns the gene IL6 and arthritic joint disease.