As our study evidently illustrated that TAX administration induced apoptosis and cell cycle arrest by modulation of expression of β-catenin in colorectal cancer cell lines (HCT116 and HT29 cells) as revealed earlier by cleavage of Caspase 3 and PARP, also by modulation of cyclin dependent kinases in HCT116 and HT29 cells after administration of TAX in a dose dependent manner. The gene discussed is CASP3; the disease is colorectal cancer.