In contrast to most studies performed in rodent models where IL-7R blockade induce broad lymphodepletion37, administration of high doses (i.e., 10 mg/Kg) of anti-IL-7Rα mAb targeting either site-1 or site 1/2b in non-human primates (here in baboons or previously by others in marmoset42 or cynomolgus monkey47) did not induce lymphopenia or significant decrease in peripheral T lymphocyte numbers. The gene discussed is IL7R; the disease is lymphopenia.