NR3C2 and infection: Investigation into effects of the MR on the temporal cascade of viral transcription found expression of IE (ICP4), early (E; UL23) and late (L; gC) genes to be significantly repressed following overexpression of the MR (IE (p = 0.008), E (p = 0.0004) and L (p = 0.0008)) as early as 2 hr post-infection (Fig. 4c).