Importantly, cancerous lesions displayed negative-to-weak staining for ATGL (mean score of 0.5; range: 0–3) (Fig. 1Ef) vs. high-positive staining in the tumor-surrounding parenchyma (mean score = 2.3; range: 0–3) (Fig. 1Eh) and far-from-lesion parenchyma (mean score = 2.25; range: 0–3) (Fig. 1Ed). The gene discussed is PNPLA2; the disease is neoplasm.