PDE8B and hypothyroidism: In thyroid tissue, we found evidence for co-localization with differential gene expression at 13 different GWAS loci: PD8EB, PRDM11, MBIP (with RP11-116N8.1 expression), NKX2-3, NSF (with WNT3 expression), IGF2BP2, FOXA2, SLC25A37, and C9orf92 for TSH; AADAT, NEK6 (with both NEK6 and PSMB7 expressions) for FT4; and TPO, PDE8B, and PDE10A for hypothyroidism (Supplementary Data 4).