We observed that these conditions are related to the development of microalbuminuria (RR 1.40; 95% CI: 1.28, 1.52) and end-stage renal disease (RR 1.31, 95% CI: 1.17, 1.47), a decreased glomerular filtration rate (ml/min) (MD -7.14; 95% CI: -12.12, -2.16), and a slightly increased albumin-creatinine ratio (mg/mmol) (MD 0.46; 95% CI: 0.03, 0.90). The gene discussed is ALB; the disease is stage 5 chronic kidney disease.