DNMT1 and pulmonary arterial hypertension: Reduced miR-140-5pcontributes, at least in part, to Dnmt1 overexpression and consequently todown-regulation of SOD2 expression and hyper-proliferation of PASMCs in PAH.Furthermore, increased miR-140-5p inhibits proliferation and promotes apoptosis anddifferentiation of PASMCs under hypoxic conditions (78).