The results showed that the expression of miR125b-2-3p was significantly lower in HCC tissues than in adjacent tissues (PmiR125b-2-3p = 0.0052), while the expression levels of lncRNAp26302, CDK1, cyclin A2, and PLK1 were significantly higher in HCC tissues than in adjacent tissues (PP26302 = 0.0255; PCCNA 2 = 0.028; PCDK 1 = 0.0171; Pplk 1 = 0.0267). The gene discussed is CCNA2; the disease is hepatocellular carcinoma.