In detail, miR-212-5p decreased cytoplasmic p53 (two-way ANOVA, MPTP: F1,18 = 5.546, p = 0.0364; genotype: F1,18 = 6.631, p = 0.0243; interaction: F1,18 = 8.773, p = 0.0119) (Figures 7L,M) and increased nuclear p53 (two-way ANOVA, MPTP: F1,18 = 13.39, p = 0.0029; genotype: F1,18 = 4.789, p = 0.0475; interaction: F1,18 = 17.62, p = 0.0010) (Figures 7L,N) in the midbrain of MPTP-induced PD mice model. The gene discussed is TP53; the disease is Parkinson disease.