GATA4 and cardiac hypertrophy: In the present study, we determined the expression of CaMKII (Figures 7A,C,F,H), CaN (Figures 7A,D,F,I), and GATA-4 (Figures 7A,E,F,J) and the nuclear translocation of NFAT-3 (Figures 7A,B,F,G), all of which are implicated in the development of cardiac hypertrophy and apoptosis and are mediated by [Ca2+]i.