These 58 candidate genes were used for predicted protein-protein interaction analysis and revealed a network with eight blast-resistant genes (Pi-d3, LOC_Os06g22460; Pi5, LOC_Os11g11810; Pi56(t), LOC_Os09g16000; Pi9, LOC_Os06g17900; Pia, LOC_Os11g11790; Pish, LOC_Os01g57340; Pit, LOC_Os01g05620; Pita, LOC_Os12g18360) and three BPH-resistant genes (Bph14, LOC_Os03g63150; Bph26, LOC_Os12g37280; BPH18, LOC_Os12g37290). The gene discussed is SERPINB5; the disease is benign prostatic hyperplasia.