Both lymphomas were very unusual because the tumor cells diffusely and strongly expressed cyclin D1 despite lacking the t(11; 14)(q13; q32) as detected by several approaches including next-generation sequencing, fluorescence <i>in situ</i> hybridization using <i>CCND1</i> break apart probe and fusion probes for t(11; 14)(q13; q32), and conventional karyotyping. This evidence concerns the gene CCND1 and lymphoma.