To be LTS versus NLTS was associated with some of the conditions registered at the time of diagnosis: female sex (29.1% vs. 14.4%, p = 0.022), median younger age [26 (22 to 29) vs. 29 (26 to 36), p < 0.0001], median CD4 cell number [397 (236 to 613) vs. 78 (31 to 280), p < 0.0001] and CD4/CD8 ratio [0.4 (0.27 to 0.73) vs. 0.24 (0.06 to 0.41), p = 0.024], HCV co‐infection (65.5% vs. 44%, p < 0.01), AIDS presentation (1.4% vs. 98.6%, p < 0.0001). Here, CD8A is linked to AIDS.