27, 28 The expression levels of three pro‐inflammatory cytokines (TNF‐α, IL‐6 and IL‐1β) were significantly up‐regulated (Figure 2A), indicating a successful establishment of bovine mastitis cell model. Consistent with the expression trend in bovine mastitic tissues, lncRNA XIST expression level was also significantly higher in inflammatory MAC‐T cells than that in normal MAC‐T cells (Figure 2B). This evidence concerns the gene IL6 and mastitis.