Of the novel in-frame fusions listed in Table 1, the following had not been previously identified in any tumor type: CTNND1-ARHGAP26, TKT-RHOA, ARFGAP2-SLC1A27, IFFO2-UBR417, PGAP3-VMP117, UBE2L318-MAPK1, ZNF292-PREX119, TACC2-PPAPDC1A20, ANXA2-MYO9A, ECT2-FABP6, LONP1-SAFB, LUC7L3-C10orf76, CLSTN1-EFCAB7, TERF2-CDH3, GTF2I-FBF1, ARMC7-PEX14, INTS12-TBCK, ELK3-NTN4, EIF4G2-UPK2, RICTOR-GHR, RNASEH2C-CFL1, ARHGAP26-NDFIP1, and IDUA-GAK (Fig. 1b). The gene discussed is CDH3; the disease is neoplasm.