The complete absence of gp91phox from macrophages is also in line with some of the infections observed in the p.Tyr2Ter homozygous individuals, like M.tuberculosis37, Legionella38, and C.albicans39, as well as the increased susceptibility of bc017643-knockout mice to S.Typhimurium and L.monocytogenes infections14. This evidence concerns the gene CYBB and infection.