SOD1 and hydrops fetalis: To evaluate the effect of HF and iron supplementation on oxidative status, we measured in serum and LV tissue: (i) concentration of an oxidative stress marker, 8-isoprostane, formed involving free radical initiated peroxidation of arachidonic acid, (ii) oxidative protein damage by the assessment of protein carbonyl (PC) as well as (iii) antioxidant enzymatic activity of total superoxide dismutase (SOD).