On the identical lines, Lin et al. (2014) [56] too observed the lack of association between CCND1 polymorphism (G870A) and head and neck cancer, however; they found that smokers carrying ‘A’ allele or ‘AA’ genotype for rs9344 SNP located on CCND1 may be at higher risk to head and neck cancer development. This evidence concerns the gene CCND1 and head and neck cancer.