This is in contrast to our previous findings in colorectal and hepatocellular carcinoma, where EGFR expression in myeloid cells was found to be essential for tumor formation (Lanaya et al, 2014; Srivatsa et al, 2017), indicating that the tumorigenic role of EGFR varies depending on the tumor and cell type. Here, EGFR is linked to hepatocellular carcinoma.