HMGCR and metabolic disease: These transcripts have been associated with metabolic disease in humans [42,43]; however, the cattle NSDHL gene has been associated with transcriptomic changes occurring during the oocyte developmental competence [44], whereas MSMO1 (together with HMG-CoA reductase and other genes involved in cholesterol synthesis) was enriched in heifers fed with different forage-to-concentrate ratios [45].