Similarly, in an MC38 cell line model of colon cancer, the addition of RT to PD-L1 blockade significantly reduced tumor growth: RT vs. RT plus PD-L1 blockade = 278.6 ± 94.20 mm vs. 27.85 ± 27.85 mm (p = 0.034) [12]. Here, CD274 is linked to malignant colon neoplasm.