RMDN3 and melanoma: Yet, if the grade of Tyrosine 176 phosphorylation is analyzed, melanocytes from dysplastic nevi displayed the highest level in Tyr 176 phosphorylated PTPIP51 compared to the Tyr176 phosphorylation status of melanocytes derived from normal nevi, exhibiting the lowest phosphorylation level and when compared to the phosphorylation state in melanocytes from malignant melanomas displaying a tyrosine phosphorylation level laying in between.