INS and Insulin resistance: Immunohistochemistry staining showed that ILG supplementation significantly suppressed insulin secretion by the pancreatic islets compared to the HFD group (Figure 3A) and ameliorated insulin resistance with simultaneous decreases in fasting blood glucose, plasma glucose, and insulin, HOMA-IR, insulin resistance predictor, intraperitoneal glucose tolerance test (IPGTT), and area under the concentration-time curve (AUC) (Figure 3B).